"In legitimately striving to improve returns to their shareholders, global companies big and small structure their affairs and businesses to minimise paying tax, while operating within the law," she told an audience at the Brookings Institution, one of America's most respected think tanks.
"Tax collectors face tremendous difficulty capturing taxes on revenue from their domestic jurisdictions.
"While such corporate behaviour is understandable, developing countries are estimated to lose between $US35 billion and $US160 billion in revenue each year.
"If all companies paid taxes on profits in the countries in which they are derived, this would largely negate need for global aid flows or development assistance," she said.
She said the total spent on development aid in 2013 was $US135 billion, less than the upper estimate of lost tax revenue.